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Some known facts about World Thalassemia Day

To raise awareness world Thalassemi Day is being observed across the world today

Policy Pulse
Publish Date: May 9 2016 2:33PM | Updated Date: May 9 2016 2:33PM

Some known facts about World Thalassemia Day

Thalassemia, a blood disorder that originated in the Mediterranean region, involves the production of abnormal amounts of haemoglobin in the body. Also called the Mediterranean anemia, this disorder is known to be most widespread in African, Mediterranean and Asian countries.

 

Dr Mandeep Singh, Sr. Consultant, Fortis Escorts Bone and Spine Institute, said, "Thalassemia is a blood disorder, which is an inherited autosomal disorder where abnormal hemoglobin is formed in the body. This is due to a variant or the missing gene that determines how the body makes hemoglobin. The result is improper transport of oxygen in the body and destruction of red blood cells. People suffering from thalassemia have less hemoglobin and fewer red blood cells which translate into anemia or anemic conditions."

 

Several after effects that a person facing Thalassemia are iron overload in the body, bone deformities and cardiovascular illnesses.

 

According to the reports, Research showed that this disease had resulted in 25,000 deaths in 2013.

 

Dr. Singh added, "Presented as anemia, thalassemia is a condition that requires repeated blood transfusion. Combination of repeated blood transfusion and chelation therapy has dramatically increased the life expectancy of thalassemic patients. On the other hand repeated blood transfusion leads to iron overload."

 

The disease can leads to frequent endocrine changes which includes Hypogonadism, Short stature, Diabetes mellitus, Hyperparathyroidism, Bony changes, Vertebral fractures and many more.

 

High occurrence of osteoporosis and osteopenia is observed in the patients. BMD (bone mineral density) is done to assess the severity of osteoporosis. Zinc and vitamin d deficiency is keenly seen in these patients frequently.

 

He further informed, "Bone mass is reduced in children. Peak bone mass is suboptimal in adults. Fracture is common in these patients. Bone pain is more common in females. Treatment usually aims at improving BMD, by the use of calcium, vitamin D and gonadal steroid replacement therapy."